From Gainesville: I-985 becomes Ga. 365 in Gainesville, Ga. Take Ga. 365 North to the Demorest-Helen exit. and turn left onto Historic Hwy. 441. HCMC is approximately 2.5 miles on left.

From Toccoa: Take Ga. 17 - Ga. 365 to Demorest-Helen exit (U.S. Historic Route 441), Turn left onto Historic Hwy. 441. HCMC is approximately 2.5 miles on left.

From Atlanta: I-85 North to I-985. I-985 becomes Ga. 365 in Gainesville, Ga. Take Ga. 365 North to Demorest-Helen exit (U.S. Historic Route 441), Left to Demorest. HCMC is approximately 2.5 miles on left.

From Greenville, S.C.: I-85 South to Ga. 17. Left to Toccoa. Take bypass Ga. 17 - Ga. 365 to Demorest-Helen exit (U.S. Historic Route 441), Left to Demorest. HCMC is approximately 2.5 miles on left.

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